Hormone Replacement Therapy with ProMD Health Columbia

Hormone Replacement Therapy (HRT) has evolved significantly, yet outdated and misleading information still prevent many men and women from receiving care that could profoundly improve their health and quality of life. At ProMD Health in Columbia, we have proudly provided hormone replacement therapy for over six years, using Evexipel® bioidentical hormone pellets to help patients restore balance and vitality—so they not only look younger, but truly feel younger.

Much of the fear surrounding HRT originated from the Women’s Health Initiative (WHI) study published in the early 2000s. Media coverage failed to distinguish synthetic hormones from bioidentical estrogen and overlooked the importance of patient age and timing. Decades of follow-up data now show that estrogen does not cause cancer. In fact, estrogen-only therapy has been shown to reduce breast cancer risk while offering protection for bone, brain, and cardiovascular health.

What is often overlooked is that women are far more likely to die from heart disease than from breast cancer. Estrogen plays a critical role in maintaining healthy blood vessels, cholesterol balance, and overall cardiovascular function. When estrogen levels decline during menopause, a woman’s risk of heart disease rises sharply. Replacing estrogen appropriately is one of the most powerful tools available to protect long-term heart health.

Equally important—but far less discussed—is testosterone’s role in women’s health. Testosterone supports energy, muscle mass, metabolism, mental clarity, mood, bone density, and libido. As women age, testosterone levels decline alongside estrogen, often contributing to fatigue, weight gain, and decreased motivation. Optimizing both estrogen and testosterone is essential for true hormonal balance and optimal outcomes.

Timing matters. Hormone therapy provides the greatest benefit when started within 10 years of menopause, allowing patients to receive the full protective effects on the heart, brain, and bones while minimizing risks.

Evexipel® bioidentical hormone pellets offer a convenient, consistent solution. The pellets are placed just beneath the skin during a quick in-office procedure that takes only minutes. Women typically receive treatment every four months; men every six months. Once inserted, pellets provide a steady, physiologic release of hormones without daily hassle. Many patients are surprised to learn this therapy costs less than $5 per day. We also use insurance for required bloodwork whenever possible and offer inexpensive self-pay options.

At ProMD Health in Columbia, we are passionate about providing thoughtful, personalized care. In addition to hormone replacement therapy, we offer medical weight loss and peptide treatments to support overall wellness, vitality, and longevity.

Hormone optimization isn’t about vanity—it’s about prevention, balance, and helping you feel your best at every stage of life.