Here in Lake Las Vegas, many women are focused on staying active, feeling strong and enjoying life, whether that means walking the trails, playing pickleball, golfing, traveling or keeping up with family and friends.
For some women, however, weight gain, increased appetite and metabolic changes can make that harder, especially during perimenopause and menopause. This is one reason GLP-1 medications such as Wegovy, Zepbound, Ozempic and Mounjaro have become so popular.
For the right patient, these medications can reduce appetite, quiet constant “food noise,” improve blood sugar and support meaningful weight loss. But they are not intended for everyone who simply wants to lose a few pounds.
In general, GLP-1 medications may be considered for adults with a BMI of 30 or higher, or a BMI of 27 or higher along with a weight-related condition such as high blood pressure, high cholesterol, prediabetes, type 2 diabetes or sleep apnea.
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BMI is only part of the decision. In my telemedicine practice, I prescribe these medications for the right patient after a careful medical evaluation. I also consider a woman’s medical history, abdominal weight gain, metabolic health, previous weight-loss efforts, medications and how her weight is affecting her energy, mobility and quality of life.
One question I hear frequently is: Why are some women having gallbladder problems after starting these medications?
Rapid weight loss itself can increase the risk of gallstones. As weight comes off, more cholesterol may enter the bile, and the gallbladder may not empty as effectively. GLP-1 medications can also slow digestion and may affect gallbladder function.
Most women taking a GLP-1 will not need their gallbladder removed. However, the risk may be greater with rapid weight loss, higher doses, longer treatment or a previous history of gallstones.
Seek medical attention for persistent pain in the upper-right abdomen, vomiting, fever, yellowing of the skin or eyes, or pain that travels to the back or right shoulder.
GLP-1 medications can be life-changing, but they work best as part of a complete lifestyle plan. Adequate protein, hydration, strength training, regular movement and medical supervision can help protect muscle, energy and long-term health while the weight comes off.
Dr. Diana Hoppe is a board-certified OB/GYN and Menopause Society Certified Practitioner who helps women over 40 feel informed, supported and confident through hormonal and metabolic changes.
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